The E6 is the European path with the large routes that crosses and connects the countries of Europe. In the prefecture of Drama it enters from the area of Kato Vrontou and exits from Paranesti, after crossing the Falakro Mountain. The lowest altitude of the route is located in Paranesti, at 120 meters, while the highest is in the Falakro, at 1800 meters. The route exceeds 90 kilometers, and the total walking time is estimated at 35-40 hours.